:root{--ink:#101c47;--muted:#566887;--blue:#0769ce;--line:#dce8f3;--pale:#f2f9ff;--shadow:0 12px 40px rgba(31,82,130,.08)}*{box-sizing:border-box}html{scroll-behavior:smooth;scroll-padding-top:95px}body{margin:0;color:var(--ink);font:16px/1.58 -apple-system,BlinkMacSystemFont,'Segoe UI',Arial,sans-serif;background:#fff}a{color:var(--blue);text-decoration:none}a:hover{text-decoration:underline}h1,h2,h3,p{margin-top:0}h1{font-size:clamp(2.3rem,4.1vw,4rem);line-height:1.08;letter-spacing:-.045em}h2{font-size:clamp(1.7rem,2.3vw,2.5rem);line-height:1.18;letter-spacing:-.035em}h3{line-height:1.25}p{color:var(--muted)}.wrap{max-width:1310px;margin:auto;padding-left:26px;padding-right:26px}.header{position:sticky;top:0;z-index:30;background:#fffffff2;backdrop-filter:blur(18px);border-bottom:1px solid #e7f0f8}.header-in{display:flex;align-items:center;gap:24px;min-height:81px}.brand{display:flex;align-items:center;gap:10px;color:var(--ink);flex-shrink:0}.brand:hover{text-decoration:none}.brand 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p{font-size:12px;line-height:1.45;margin-bottom:16px}.arrow{border:1px solid #a9d9ff;width:29px;height:29px;border-radius:50%;display:grid;place-items:center;margin-top:auto;color:var(--blue)}.stats{margin-top:10px;margin-bottom:20px;background:linear-gradient(100deg,#eef8ff,#f8fcff);border-radius:16px;display:grid;grid-template-columns:1fr 300px;gap:20px;padding-top:25px;padding-bottom:25px}.stats h2{font-size:22px;margin:7px 0}.stats p{margin:0;font-size:13px}.stat-num{border-left:1px solid #d5e7f5;padding-left:27px;display:flex;flex-direction:column;justify-content:center}.stat-num strong{font-size:36px;color:var(--blue);line-height:1.2}.stat-num span,.stat-num a{font-size:12px}.research-band{background:#f5faff;padding:38px 0 42px}.sectionhead{display:flex;align-items:end;justify-content:space-between;gap:25px;margin-bottom:22px}.sectionhead h2{margin:7px 0}.sectionhead 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p{font-size:14px}.small-link{font-weight:650;font-size:14px}.professional{padding-top:52px;padding-bottom:35px}.guides{display:grid;grid-template-columns:1fr 1fr;gap:18px;margin-bottom:54px}.guide{padding:26px}.guide h3{font-size:22px;margin:12px 0}.guide p{min-height:100px}.trial-detail{scroll-margin-top:100px;background:#fff;border:1px solid var(--line);border-radius:16px;padding:26px;margin-bottom:17px;display:grid;grid-template-columns:1fr 360px;gap:28px;align-items:center}.trial-detail:has(img){min-height:260px}.trial-detail h3{font-size:26px;margin:9px 0}.trial-detail p{color:var(--muted);max-width:780px}.trial-detail img{width:100%;border-radius:10px;border:1px solid #edf1f6}.contact-layout{display:grid;grid-template-columns:minmax(0,1fr) 340px;gap:25px;padding-top:50px;padding-bottom:75px}.formcard{padding:30px}.formcard label{display:flex;flex-direction:column;font-size:14px;font-weight:650;gap:7px;margin:18px 0}.formcard input,.formcard select,.formcard textarea{width:100%;font:inherit;border:1px solid #b9cfdf;border-radius:9px;padding:11px 12px;color:var(--ink);background:#fff}.formcard .check{flex-direction:row;align-items:start;font-weight:400}.formcard .check input{width:auto;margin-top:6px}.footer{background:#10254a;color:#e8f3ff;padding-top:35px}.foot-inner{display:flex;justify-content:space-between;gap:30px}.foot-inner p{max-width:400px;font-size:13px;color:#bac9df}.foot-inner div:nth-child(2){display:flex;gap:24px}.footer a{color:#c6e2ff;font-size:13px}.foot-bottom{font-size:12px;border-top:1px solid #2c4364;color:#b2c5df;padding-top:20px;padding-bottom:25px;margin-top:20px}@media(max-width:1120px){.header-in{gap:10px}.header nav a{font-size:11px;padding:9px 6px}.hero-grid{grid-template-columns:1.15fr .85fr}.hero-notes{grid-column:1/-1;grid-template-columns:1fr 1fr}.note{display:grid;grid-template-columns:55px 1fr;column-gap:12px}.note .icon-circle{grid-row:1/4}.cards{grid-template-columns:repeat(3,1fr)}.hero-art .heart-svg{max-height:380px}}@media(max-width:760px){.wrap{padding-left:18px;padding-right:18px}.header-in{min-height:70px;flex-wrap:wrap;justify-content:space-between}.brand strong{font-size:22px}.brand small{font-size:10px}.head-btn{display:none}.menu-toggle{display:block}.header nav{display:none;width:100%;flex-basis:100%;flex-direction:column;align-items:stretch;padding:0 0 12px}.header nav.open{display:flex}.header nav a{font-size:15px;padding:12px}.hero-grid{display:flex;flex-direction:column;align-items:stretch;min-height:auto;padding-top:35px}.hero-copy h1{font-size:clamp(2.2rem,9vw,3.6rem)}.hero-art{align-self:center;max-width:390px}.heart-svg{width:100%;transform:none}.hero-notes{grid-template-columns:1fr 1fr}.benefits{flex-direction:column;gap:14px}.cards{grid-template-columns:repeat(2,minmax(0,1fr))}.navcard{min-height:210px;padding:15px}.navcard h3{font-size:15px}.stats{grid-template-columns:1fr}.stat-num{border-left:0;border-top:1px solid #d5e7f5;padding:15px 0 0}.research-grid,.guides,.trial-detail,.article-layout,.contact-layout{grid-template-columns:1fr}.trial-detail{gap:12px}.trial-detail img{max-width:550px}.side{flex-direction:row}.sidecard{flex:1}.cta,.sectionhead{flex-direction:column;align-items:start}.cta{padding:27px 23px}.lede{font-size:17px}.inner-hero{padding:45px 0 37px}.prose p,.prose li{font-size:16px}.foot-inner{flex-direction:column}.foot-inner div:nth-child(2){flex-wrap:wrap}}@media(max-width:440px){.hero-notes{grid-template-columns:1fr}.cards{gap:8px}.navcard{min-height:240px}.actions .btn{width:100%}.side{flex-direction:column}.cta .btn{width:100%}.research-band{padding:30px 0}}

/* Design-locked October 2026 homepage: approved screenshot proportions */
:root{--ink:#091943;--muted:#596c90;--blue:#0866c8}
.wrap{max-width:1260px;padding-left:18px;padding-right:18px}
.header-in{min-height:59px;gap:13px}.header{box-shadow:0 2px 11px #b7d1ed16}.brand strong{font-size:25px}.brand small{font-size:10px}.brand em{color:#081942}.logo{font-size:39px;color:#fa626e}.header nav a{font-size:11px;padding:9px 9px}.head-btn{padding:12px 22px;font-size:12px}
.reference-hero{background:linear-gradient(95deg,#effaff,#f8fcff 64%,#eef8fe);overflow:hidden}
.reference-grid{min-height:363px;display:grid;grid-template-columns:minmax(0,41%) minmax(0,38%) minmax(0,21%);gap:0;position:relative}
.reference-intro{padding:29px 0 23px;z-index:2}.reference-intro h1{font-size:clamp(38px,4vw,51px);line-height:1.02;letter-spacing:-.046em;margin:0 0 15px}.reference-lead{font-size:19px;line-height:1.2;font-weight:650;margin:0 0 19px;max-width:450px}
.reference-heart{min-width:0;position:relative;overflow:visible;min-height:365px}.reference-heart img{height:365px;width:475px;max-width:none;object-fit:contain;position:absolute;top:50%;left:-10px;transform:translateY(-50%)}
.reference-aside{z-index:2;display:flex;flex-direction:column;justify-content:center;gap:12px;padding:16px 0 16px 9px}.fact-card{min-height:141px;display:grid;grid-template-columns:63px 1fr;gap:8px;border:1px solid #d8e8f7;border-radius:11px;padding:15px 11px;background:#ffffffcb;color:var(--ink)}.fact-card:hover{text-decoration:none;box-shadow:0 8px 25px #1e6cae15}.fact-card h3{font-size:14px;line-height:1.18;margin:3px 0 10px}.fact-card p{font-size:11px;line-height:1.32;margin:0 0 8px}.fact-card span:not(.fact-icon){font-size:11px;color:#0765bf}.fact-icon{width:52px;height:52px;background:#cdeaff;border-radius:50%;display:grid;place-items:center;font-size:25px;color:#0866be}
.micro-benefits{display:grid;grid-template-columns:1fr 1.05fr 1.1fr;gap:9px;margin-bottom:24px}.micro-benefits div{display:flex;align-items:flex-start;gap:7px;font-size:10px;line-height:1.35;color:#526785}.micro-icon{display:grid;place-items:center;flex-shrink:0;width:35px;height:35px;border-radius:50%;background:#c9eafb;color:#0e477c;font-size:19px}.reference-actions{display:flex;gap:11px}.reference-actions .btn{font-size:12px;padding:11px 19px;white-space:nowrap;border-radius:8px}
.show-cards{display:grid;grid-template-columns:repeat(6,minmax(0,1fr));gap:10px;margin-top:11px;margin-bottom:11px}.show-card{border:1px solid #d8e8f6;border-radius:8px;overflow:hidden;min-height:222px;display:flex;flex-direction:column;color:var(--ink);background:#fff}.show-card:hover{text-decoration:none;box-shadow:0 10px 26px #1462ab15;transform:translateY(-2px)}.show-card img{height:83px;width:100%;object-fit:cover;object-position:center}.show-card-body{padding:5px 14px 10px;display:flex;flex-direction:column;flex:1}.show-card h3{font-size:15px;line-height:1.08;margin:4px 0 8px}.show-card p{font-size:11px;line-height:1.28;margin:0 0 10px}.round-arrow{display:grid;place-items:center;border:1px solid #afd9f8;border-radius:50%;width:30px;height:30px;color:#0a65c2;margin-top:auto}
.worldwide{display:grid;grid-template-columns:1.8fr 1fr 1fr 1.05fr .85fr;align-items:center;gap:0;background:#eff8fe;border-radius:11px;min-height:105px;margin-bottom:13px;padding-top:13px;padding-bottom:13px}.world-text,.world-number,.world-region{display:flex;gap:11px;padding:0 13px;border-right:1px solid #d7e9f6;align-items:flex-start}.world-text h3{font-size:13px;margin:1px 0 7px}.world-text p,.world-number p{font-size:11px;line-height:1.4;margin:0}.world-icon{font-size:29px;color:#1077c8}.world-number .flag,.world-region>span{font-size:30px}.world-number strong{font-size:21px;line-height:1.2}.world-number small,.world-region small{font-size:10px;display:block;line-height:1.25;color:#627897}.world-region b{display:block;font-size:13px;margin:2px 0 5px}.world-cta{font-size:11px;line-height:1.45;padding:14px 10px;background:#d6edfc;border-radius:7px;margin-left:10px}
.studies-strip{display:grid;grid-template-columns:38% 62%;gap:0;background:#f5fafe;border-radius:10px;min-height:235px;padding-top:12px;padding-bottom:12px;margin-bottom:12px}.studies-intro{padding:15px 14px}.studies-intro h2{font-size:20px;letter-spacing:-.025em;margin:0 0 9px}.studies-intro p{font-size:13px;line-height:1.4;max-width:400px;margin-bottom:21px}.studies-intro .btn{padding:11px 20px;font-size:12px}.studies-list{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:8px}.study{background:#fff;border:1px solid #d7e8f4;border-radius:9px;color:var(--ink);padding:10px;display:flex;flex-direction:column;min-width:0}.study:hover{text-decoration:none;box-shadow:0 8px 18px #1a62a519}.study-meta b{display:block;font-size:11px;line-height:1.15}.study-meta small{display:block;font-size:10px;color:#61718c}.study img{width:100%;height:65px;object-fit:contain;margin:4px 0}.study strong{font-size:15px;color:#15964f;line-height:1.25;margin-top:auto}.study p{font-size:10px;line-height:1.25;margin:5px 0}.study-link{font-size:10px;color:#0967c1;margin-top:auto}.study-symbol{height:69px;display:flex;flex-direction:column;align-items:center;justify-content:center}.study-symbol span{font-size:9px;color:#5e7396;text-align:center;line-height:1.2}.study-symbol svg{width:110px;height:33px}
.consultation-banner{background:linear-gradient(95deg,#ebf7fd,#f8fcff);margin-bottom:0}.consultation-inner{min-height:142px;display:grid;grid-template-columns:200px 1fr 1.2fr;gap:18px;align-items:center}.consultation-art{height:142px;display:grid;place-items:center;font-size:105px;color:#c3ddef;opacity:.75}.consultation-main h2{font-size:18px;margin:0 0 7px;letter-spacing:-.02em}.consultation-main p{font-size:12px;line-height:1.4;margin-bottom:10px}.consultation-buttons{display:flex;gap:9px}.consultation-buttons .btn{padding:10px 16px;font-size:11px}.consultation-perks{display:flex;gap:12px;border-left:1px solid #d5e7f3;padding-left:15px}.consultation-perks div{font-size:27px;color:#0d75c9;display:flex;align-items:center;gap:6px;flex:1}.consultation-perks span{font-size:10px;color:#566d87;line-height:1.3}
@media(max-width:1100px){.reference-grid{grid-template-columns:43% 36% 21%}.reference-heart img{width:415px;left:-26px}.reference-intro h1{font-size:42px}.micro-benefits{gap:5px}.micro-benefits div{font-size:9px}.reference-actions{flex-wrap:wrap}.fact-card{grid-template-columns:1fr;padding:12px}.fact-icon{width:37px;height:37px}.show-card h3{font-size:13px}.show-card-body{padding:6px 9px 10px}.worldwide{grid-template-columns:2fr 1fr 1fr}.world-region:nth-of-type(4),.world-cta{display:none}.consultation-inner{grid-template-columns:100px 1fr}.consultation-perks{display:none}}
@media(max-width:760px){.reference-grid{display:flex;flex-direction:column}.reference-intro{padding:28px 0 0}.reference-intro h1{font-size:clamp(35px,8vw,52px)}.reference-lead{font-size:17px}.micro-benefits{grid-template-columns:repeat(3,1fr)}.micro-benefits div{font-size:10px}.reference-heart{height:285px;align-self:center;width:100%;max-width:450px}.reference-heart img{width:440px;max-width:100%;height:290px;position:static;object-fit:contain}.reference-aside{display:grid;grid-template-columns:1fr 1fr;padding:0 0 16px}.fact-card{min-height:155px}.show-cards{grid-template-columns:repeat(3,minmax(0,1fr))}.worldwide{grid-template-columns:1fr 1fr}.world-text{grid-column:1/-1;padding-bottom:15px;margin-bottom:12px;border-bottom:1px solid #d9eaf5}.world-region{display:none}.world-number{border:0}.world-cta{display:block;text-align:center}.studies-strip{grid-template-columns:1fr}.studies-list{grid-template-columns:repeat(2,1fr)}.consultation-inner{grid-template-columns:1fr;padding-top:22px;padding-bottom:22px}.consultation-art{display:none}}
@media(max-width:460px){.reference-actions{flex-direction:column}.reference-actions .btn{width:100%}.reference-aside{grid-template-columns:1fr}.fact-card{display:grid;grid-template-columns:53px 1fr;min-height:auto}.show-cards{grid-template-columns:repeat(2,minmax(0,1fr))}.show-card{min-height:225px}.worldwide{grid-template-columns:1fr}.world-number{border-bottom:1px solid #d9eaf5;padding-bottom:12px}.world-cta{margin:10px}.micro-benefits{gap:5px}.micro-icon{height:30px;width:30px}.reference-heart{height:245px}.reference-heart img{height:250px}.studies-list{gap:7px}.study{padding:8px}}

/* LAA Closure v3 — approved logo on all pages */
.brand{gap:9px;min-width:235px;flex-shrink:0}
.brand-symbol{display:block;width:53px;height:53px;object-fit:contain;flex-shrink:0}
.brand-label{display:block}
.brand .brand-label strong{font-size:15px;line-height:1.12;letter-spacing:-.025em;font-weight:800;color:#092451;white-space:nowrap}
.brand .brand-label small{font-size:11px;line-height:1.35;color:#8390a5;letter-spacing:.015em;margin-top:3px}
@media(max-width:1200px){.header-in{flex-wrap:wrap;justify-content:space-between}.menu-toggle{display:block}.header nav{display:none;width:100%;flex-basis:100%;flex-direction:column;align-items:stretch;padding:0 0 12px;order:5}.header nav.open{display:flex}.header nav a{font-size:15px;padding:12px}.head-btn{margin-left:auto}}
@media(max-width:760px){.header-in{gap:9px}.brand{min-width:0}.brand-symbol{height:46px;width:46px}.brand .brand-label strong{font-size:13px}.brand .brand-label small{font-size:10px}.head-btn{display:none}}

/* v5: limited content and type corrections over original v3 layout */
.reference-intro h1{font-size:clamp(34px,3.25vw,44px)}
.reference-lead{font-size:17px;font-weight:600}
.inner-hero h1{font-size:clamp(29px,3vw,45px)}
.inner-hero .lede{font-size:17px}
.prose p,.prose li{font-size:15px}
.reference-heart img{object-fit:cover;object-position:center center;border-radius:18px;mix-blend-mode:multiply}
.micro-icon{font-size:15px;font-weight:800}
.fact-icon{font-size:17px;font-weight:800;text-align:center}
.consultation-inner{grid-template-columns:1fr 1.2fr}
.consultation-perks div{font-size:20px}
@media(max-width:1100px){.consultation-inner{grid-template-columns:1fr}}
@media(max-width:760px){.reference-intro h1{font-size:clamp(32px,7vw,44px)}.reference-lead{font-size:16px}.reference-heart img{object-fit:cover}}

/* v6: two evidence figures added to v5 without altering original layout */
.hero-evidence{display:grid;grid-template-columns:1fr 1fr;gap:0;margin:15px 0 19px;max-width:465px}
.hero-evidence-item{min-width:0;padding:0 17px 0 0}
.hero-evidence-item+.hero-evidence-item{border-left:1px solid #b7d3ed;padding:0 0 0 18px}
.hero-evidence strong{display:block;color:#0864ca;font-weight:760;font-size:clamp(32px,3.45vw,53px);line-height:1.06;letter-spacing:-.045em;white-space:nowrap}
.hero-evidence p{font-size:clamp(11px,1.06vw,14px);line-height:1.46;margin:9px 0 0;color:#526887}
.hero-evidence p span{display:inline-block;margin-top:3px}
@media(max-width:1100px){.hero-evidence strong{font-size:clamp(28px,3.2vw,40px)}.hero-evidence p{font-size:11px}.hero-evidence-item{padding-right:10px}.hero-evidence-item+.hero-evidence-item{padding-left:11px}}
@media(max-width:760px){.hero-evidence{max-width:500px}.hero-evidence strong{font-size:clamp(33px,7vw,50px)}.hero-evidence p{font-size:12px}}
@media(max-width:380px){.hero-evidence strong{font-size:30px}.hero-evidence p{font-size:11px}}


/* v8: hero tightened and right fact card de-duplicated */
.reference-grid{padding-top:14px;padding-bottom:14px}
.reference-intro h1{margin:0 0 12px}
.reference-lead{margin-bottom:10px;font-size:16px;line-height:1.28}
.hero-evidence{max-width:540px;margin:10px 0 14px}
.hero-evidence strong{font-size:clamp(28px,2.75vw,44px);line-height:1.02}
.hero-evidence-item:nth-child(2) strong{font-size:clamp(26px,2.6vw,40px)}
.hero-evidence p{font-size:clamp(10px,0.95vw,12.5px);line-height:1.34;margin:7px 0 0}
.micro-benefits{margin-bottom:18px}
.fact-card .fact-icon{font-size:15px}
@media(max-width:1100px){.hero-evidence{max-width:500px}.hero-evidence strong{font-size:clamp(25px,2.9vw,36px)}.hero-evidence-item:nth-child(2) strong{font-size:clamp(23px,2.7vw,34px)}.hero-evidence p{font-size:10.5px;line-height:1.3}}
@media(max-width:760px){.reference-grid{padding-top:10px;padding-bottom:12px}.hero-evidence{max-width:100%;margin:12px 0 14px}.hero-evidence strong{font-size:clamp(30px,7vw,42px)}.hero-evidence-item:nth-child(2) strong{font-size:clamp(28px,6.5vw,38px)}.hero-evidence p{font-size:11px}}


/* v10: right hero cards equal height and aligned to image */
.reference-aside{display:grid;grid-template-rows:1fr 1fr;gap:20px;padding:0 0 0 9px;align-self:stretch;height:365px}
.fact-card{min-height:0;height:100%;align-content:start}
.fact-card h3{font-size:15px;line-height:1.12;margin:3px 0 8px}
.fact-card p{font-size:11px;line-height:1.34;margin:0 0 8px}
@media(max-width:1100px){.reference-aside{height:auto;align-self:start}}
@media(max-width:760px){.reference-aside{height:auto;padding:0 0 16px;gap:12px}}


/* v11: constrain right cards strictly within hero image height */
.reference-grid{align-items:start}
.reference-heart{min-height:340px}
.reference-heart img{height:340px;top:50%;transform:translateY(-50%)}
.reference-aside{align-self:start;height:340px;grid-template-rows:repeat(2,minmax(0,1fr));gap:14px;padding:0 0 0 9px;overflow:hidden}
.fact-card{height:100%;min-height:0;padding:14px 14px 12px;overflow:hidden}
.fact-card p{font-size:10.5px;line-height:1.28;margin:0 0 7px}
.fact-card h3{font-size:14px;line-height:1.08;margin:2px 0 7px}
.fact-card span:not(.fact-icon){font-size:10.5px}
@media(max-width:1100px){.reference-heart{min-height:320px}.reference-heart img{height:320px}.reference-aside{height:320px;gap:12px}}
@media(max-width:760px){.reference-grid{align-items:stretch}.reference-heart{min-height:auto}.reference-heart img{height:290px;transform:none}.reference-aside{height:auto;overflow:visible}}


/* v12: lower center image and right cards to align with left column */
.reference-heart{margin-top:22px}
.reference-aside{margin-top:22px}
@media(max-width:1100px){.reference-heart,.reference-aside{margin-top:16px}}
@media(max-width:760px){.reference-heart,.reference-aside{margin-top:0}}


/* v13: align left action buttons with bottom edge of center image */
.reference-heart{min-height:372px}
.reference-heart img{height:372px}
.reference-aside{height:372px}
@media(max-width:1100px){.reference-heart{min-height:350px}.reference-heart img{height:350px}.reference-aside{height:350px}}
@media(max-width:760px){.reference-heart{min-height:auto}.reference-aside{height:auto}}


/* v14: nudge center image and right cards slightly upward */
.reference-heart{margin-top:12px}
.reference-aside{margin-top:12px}
@media(max-width:1100px){.reference-heart,.reference-aside{margin-top:10px}}
@media(max-width:760px){.reference-heart,.reference-aside{margin-top:0}}


/* v15: nudge center image and right cards slightly downward */
.reference-heart{margin-top:18px}
.reference-aside{margin-top:18px}
@media(max-width:1100px){.reference-heart,.reference-aside{margin-top:14px}}
@media(max-width:760px){.reference-heart,.reference-aside{margin-top:0}}

/* v16: exact shared lower edge of three hero columns on desktop.
   Keep the content and artwork dimensions from v15 unchanged. */
@media (min-width:761px){
  .reference-grid{align-items:end}
  .reference-intro{padding-bottom:0}
  .reference-heart,.reference-aside{margin-top:0;align-self:end}
}

/* v17: align the background edges of both lower sections with six navigation cards. */
.worldwide,.studies-strip{width:calc(100% - 36px);max-width:1224px;margin-left:auto;margin-right:auto}

/* v25: predictable navigation, accessible controls and responsive corrections */
html{scroll-padding-top:var(--header-offset,80px)}
[id]{scroll-margin-top:0}
.skip-link{position:fixed;top:8px;left:12px;z-index:100;background:#fff;padding:10px 14px;border:2px solid var(--blue);border-radius:8px;transform:translateY(-160%)}
.skip-link:focus{transform:none}
a:focus-visible,button:focus-visible,input:focus-visible,textarea:focus-visible,select:focus-visible,summary:focus-visible{outline:3px solid #0872d2;outline-offset:3px}
.info-green{background:#edf8f0;border-left-color:#32985e}
.info-green b{color:#1d663b}
.info-green a{color:#1b7040;font-weight:650}
.trial-detail:not(:has(img)){grid-template-columns:1fr}
.guide p{min-height:0}
.prose,.guide,.sidecard,.trial-detail,.formcard{overflow-wrap:anywhere}
.formcard textarea{resize:vertical;min-height:140px}
#form-status{min-height:24px}
#letter-preview[hidden]{display:none}
#letter-preview{margin-top:24px}
#letter-text{min-height:220px}
.hero-evidence p a{color:inherit;text-decoration:underline;text-underline-offset:2px}
@media(max-width:1200px){.header nav.open{max-height:calc(100dvh - 90px);overflow-y:auto}}
@media(max-width:760px){
 .reference-heart{height:290px;min-height:0;margin:0;max-width:450px}
 .reference-heart img{height:290px;width:100%;max-width:100%;position:static;transform:none;object-fit:contain}
 .reference-aside{height:auto;grid-template-rows:auto;padding:0 0 16px;overflow:visible;align-items:stretch}
 .fact-card{height:auto;overflow:visible;min-height:0}
 .fact-card p,.fact-card span:not(.fact-icon){font-size:12px;line-height:1.4}
 .fact-card h3{line-height:1.2}
 .reference-lead{line-height:1.4}
 .micro-benefits div{font-size:11px;line-height:1.4}
 .inner-hero{padding:30px 0 28px}
 .article-layout,.professional{padding-top:30px}
 .contact-layout{padding-top:30px;padding-bottom:40px}
 .formcard{padding:22px 18px}
 .formcard input,.formcard select,.formcard textarea{font-size:16px}
 .guide,.trial-detail{padding:22px}
 .guides{margin-bottom:32px}
 .worldwide{grid-template-columns:1fr 1fr 1fr}
 .world-text{grid-column:1/-1}
 .world-number{padding:0 8px;gap:6px;border:0;min-width:0}
 .world-number strong{font-size:19px}
 .world-number .flag{font-size:22px}
 .world-number p{font-size:11px}
 .world-cta{grid-column:1/-1;margin:12px 8px 0}
}
@media(max-width:460px){
 .reference-heart,.reference-heart img{height:250px}
 .worldwide{grid-template-columns:1fr}
 .world-number{padding:12px 8px;border-bottom:1px solid #d9eaf5}
 .world-number strong{font-size:22px}
 .brand .brand-label small{max-width:200px;white-space:normal}
 .show-card h3{font-size:14px;line-height:1.3}
 .show-card p{font-size:12px;line-height:1.4}
}
@media(max-width:360px){
 .brand-symbol{width:36px;height:36px}
 .brand{gap:6px}
 .brand .brand-label strong{font-size:12px}
 .brand .brand-label small{max-width:175px;font-size:9px}
 .menu-toggle{font-size:20px;padding:7px 10px}
 .header-in{gap:6px}
 .studies-list{grid-template-columns:1fr}
}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}*{transition:none!important}}
@media(max-width:1320px){
 .header-in{flex-wrap:wrap;justify-content:space-between}
 .menu-toggle{display:block}
 .header nav{display:none;width:100%;flex-basis:100%;flex-direction:column;align-items:stretch;padding:0 0 12px;order:5}
 .header nav.open{display:flex;max-height:calc(100dvh - 90px);overflow-y:auto}
 .header nav a{font-size:15px;padding:12px}
 .head-btn{margin-left:auto}
}
.inner-hero h1,.cta h2{overflow-wrap:anywhere}
@media(min-width:761px) and (max-width:1100px){
 .reference-grid{grid-template-columns:minmax(0,55%) minmax(0,45%)}
 .reference-heart{width:100%;height:350px;min-height:350px}
 .reference-heart img{width:100%;height:350px;left:0}
 .reference-aside{grid-column:1/-1;grid-template-columns:1fr 1fr;grid-template-rows:auto;height:auto;padding:0;margin-top:18px;overflow:visible}
 .fact-card{grid-template-columns:42px minmax(0,1fr);height:auto;overflow:visible;align-items:start}
 .fact-card .fact-icon{width:37px;height:37px}
 .fact-card p{font-size:12px;line-height:1.4}
}
h2{overflow-wrap:anywhere}
.micro-icon svg,.world-icon svg,.flag svg{display:block;width:100%;height:100%}
.world-icon{display:block;width:29px;height:29px;flex-shrink:0}
.flag{display:block;width:30px;height:22px;flex-shrink:0}

/* v26: illustrated reading pages */
.studies-intro .v24-figure-note{margin-top:22px!important}
.learn-overview{display:grid;grid-template-columns:1fr 1fr;gap:42px;align-items:center;padding-top:38px;padding-bottom:38px}
.learn-overview h2{font-size:30px;line-height:1.2;margin:12px 0 18px;max-width:570px}
.learn-overview>div>p{font-size:18px;max-width:560px;margin-bottom:0}
.anatomy{margin:0;background:linear-gradient(130deg,#f3f9ff,#fff6f4);border:1px solid #ddeaf3;border-radius:22px;padding:16px 22px}
.anatomy svg{display:block;width:100%;height:auto;max-height:330px;font-family:Arial,sans-serif}
.anatomy figcaption{font-size:12px;color:#65758d;text-align:center;line-height:1.5;margin:8px 0 2px}
.learn-layout{padding-top:10px;padding-bottom:28px;gap:36px;grid-template-columns:minmax(0,1fr) 275px}
.learn-layout .prose{max-width:none}
.learn-chapter{background:#fff;border:1px solid #dce8f3;border-radius:18px;padding:28px 30px;margin:0 0 20px;box-shadow:0 5px 22px #284e7310}
.learn-chapter h2,.prose .learn-chapter h2{margin:0 0 18px;font-size:26px;line-height:1.25}
.learn-chapter p:last-child{margin-bottom:0}
.learn-chapter .anatomy{margin:20px 0}
.learn-tiles{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px;margin:20px 0}
.learn-tile{background:#f3f9fd;border:1px solid #dbe9f3;border-radius:14px;padding:20px 17px;min-width:0}
.learn-tile h3{font-size:17px;line-height:1.3;margin:12px 0 9px}
.learn-tile p,.prose .learn-tile p{font-size:14px;line-height:1.55;margin:0}
.learn-icon{display:grid;place-items:center;color:#2179b6;width:44px;height:44px;background:#e1f0fa;border-radius:12px}
.learn-icon svg{width:32px;height:32px}
.learn-overview>.learn-tiles{grid-template-columns:1fr;margin:0;gap:10px}
.learn-overview>.learn-tiles .learn-tile{display:grid;grid-template-columns:48px 1fr;column-gap:15px;padding:16px 20px}
.learn-overview>.learn-tiles .learn-icon{grid-row:1/3}
.learn-overview>.learn-tiles h3{margin:0 0 5px}
.chapter-nav a{display:block;font-size:14px;line-height:1.45;padding:12px 0;border-bottom:1px solid #e5edf5}
.chapter-nav a:last-child{border-bottom:0;padding-bottom:0}
.chapter-nav .eyebrow{display:block;margin-bottom:6px}
.source-fold{background:#f2f5f8;border:1px solid #e0e5eb;border-radius:12px;padding:18px 22px;margin:0 0 40px;max-width:890px;font-size:14px}
.source-fold summary{cursor:pointer;font-weight:650;color:#44516b}
.source-fold p{margin:15px 0 10px}
.section-jumps{display:flex;flex-wrap:wrap;gap:10px;margin-bottom:24px}
.section-jumps a{font-size:14px;background:#edf7fe;border:1px solid #d6e7f6;border-radius:10px;padding:10px 16px}
.professional{padding-top:12px}
.professional .learn-chapter{margin-bottom:30px}
.referral-grid{display:grid;grid-template-columns:1fr 1fr;gap:28px}
.referral-grid h3{font-size:19px}
.referral-grid ul{padding-left:20px;color:var(--muted)}
.referral-grid li{margin-bottom:10px}
@media(min-width:1321px){.header-in{gap:10px}.header nav a{padding-left:7px;padding-right:7px;font-size:11px}.head-btn{padding-left:16px;padding-right:16px}}
@media(max-width:1000px){.learn-layout{grid-template-columns:minmax(0,1fr) 230px;gap:22px}.learn-overview{gap:25px}.learn-chapter{padding:24px}.learn-chapter .learn-tiles{grid-template-columns:1fr}.learn-overview h2{font-size:27px}}
@media(max-width:760px){.learn-overview{grid-template-columns:1fr;gap:22px;padding-top:26px;padding-bottom:26px}.learn-overview>div>p{font-size:17px}.learn-layout{grid-template-columns:1fr;padding-top:0;gap:12px}.learn-layout .side{display:grid;grid-template-columns:1fr}.learn-chapter{padding:22px 19px;border-radius:14px}.learn-chapter h2,.prose .learn-chapter h2{font-size:23px}.learn-tiles{grid-template-columns:1fr}.learn-tile{padding:18px}.anatomy{padding:10px 12px}.referral-grid{grid-template-columns:1fr;gap:15px}.learn-overview h2{font-size:26px}.source-fold{padding:16px;margin-bottom:28px}.professional .learn-chapter{padding:22px 19px}}
@media print{.chapter-nav,.section-jumps{display:none}.learn-overview,.learn-layout{display:block}.learn-chapter{box-shadow:none;break-inside:avoid}.source-fold{display:none}}

/* v27: compact identity, project information and preparation route */
.brand{min-width:210px}.brand .brand-label small{font-size:12px;letter-spacing:.08em;color:#597995;margin-top:5px}
.header nav a{padding-left:7px;padding-right:7px}
.project-route{display:grid;gap:12px}.project-route>div{background:#f2f8fd;border:1px solid #dce8f3;border-radius:16px;padding:20px 20px 20px 76px;position:relative}.project-route span{position:absolute;left:18px;top:20px;color:#0872d2;font-size:23px;font-weight:750}.project-route strong{font-size:18px}.project-route p{margin:6px 0 0;font-size:15px}
.prep-overview{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:18px;padding-top:32px;padding-bottom:30px}.prep-card{background:linear-gradient(135deg,#eff8ff,#f8fbfd);border:1px solid #dce8f3;border-radius:18px;padding:24px;min-width:0}.prep-number{display:grid;place-items:center;width:44px;height:44px;background:#deeffd;color:#0872d2;border-radius:12px;font-weight:750;font-size:20px;margin-bottom:18px}.prep-card h2{font-size:23px;margin-bottom:10px}.prep-card p{margin-bottom:0;font-size:16px}
.exam-row{display:grid;grid-template-columns:58px minmax(0,1fr);gap:18px;margin:24px 0}.exam-symbol{display:grid;place-items:center;width:58px;height:58px;background:#e8f4fc;border-radius:16px;color:#1b77b5;font-size:16px;font-weight:700}.exam-row h3{margin:0 0 9px;font-size:20px}.exam-row p{margin-bottom:0}.document-checklist{list-style:none;padding:0}.document-checklist li{position:relative;padding:13px 0 13px 30px;border-bottom:1px solid #e5eef5}.document-checklist li:before{content:'✓';position:absolute;left:0;color:#278856;font-weight:700}
@media(max-width:1320px){.header nav a{padding:12px}.brand{min-width:0}}
@media(max-width:760px){.prep-overview{grid-template-columns:1fr;gap:12px;padding-top:24px}.prep-card{padding:20px;display:grid;grid-template-columns:44px minmax(0,1fr);column-gap:16px}.prep-number{grid-row:1/3;margin:0}.prep-card h2{font-size:21px}.prep-card p{font-size:15px}.exam-row{grid-template-columns:44px minmax(0,1fr);gap:12px}.exam-symbol{width:44px;height:44px;font-size:13px}.exam-row h3{font-size:19px}.brand .brand-label small{font-size:10px}.project-route>div{padding:18px 18px 18px 65px}.project-route span{left:16px;font-size:20px}}
/* v28: consultation topic picker */
.contact-layout.contact-single{grid-template-columns:minmax(0,780px);justify-content:center}
.topic-field{position:relative;margin-bottom:18px}.topic-field>label{display:block;margin-bottom:8px}
.topic-trigger{display:flex;align-items:center;justify-content:space-between;gap:16px;width:100%;padding:16px 18px;border:1px solid #cbdfee;border-radius:14px;background:linear-gradient(120deg,#f2f9ff,#fff);color:#183653;font:inherit;text-align:left;cursor:pointer;box-shadow:0 3px 10px #163a6310;transition:border-color .2s,box-shadow .2s}
.topic-trigger:after{content:'';width:8px;height:8px;flex:0 0 8px;border-right:2px solid #0872d2;border-bottom:2px solid #0872d2;transform:rotate(45deg);margin:0 3px 5px 0;transition:transform .2s}
.topic-trigger[aria-expanded=true]:after{transform:rotate(225deg);margin-top:7px}.topic-trigger:hover{border-color:#78b5e6}.topic-trigger:focus-visible{outline:3px solid #91c9f4;outline-offset:3px}
.topic-options{position:absolute;top:calc(100% + 8px);left:0;right:0;z-index:20;padding:8px;border:1px solid #d7e8f5;border-radius:18px;background:#fff;box-shadow:0 16px 40px #183a6326}.topic-options[hidden]{display:none}
.topic-option{position:relative;display:block;width:100%;padding:14px 42px 14px 14px;border:0;border-radius:11px;background:#fff;color:#244765;font:inherit;line-height:1.45;text-align:left;cursor:pointer}.topic-option+.topic-option{margin-top:4px}.topic-option:hover,.topic-option:focus-visible{background:#f0f7fd;outline:2px solid #a8d2f1;outline-offset:-2px}.topic-option[aria-selected=true]{background:#e8f4ff;color:#0865b1;font-weight:650}.topic-option[aria-selected=true]:after{content:'✓';position:absolute;right:16px;top:50%;transform:translateY(-50%);font-size:20px;color:#0872d2}
@media(max-width:600px){.topic-trigger{padding:14px;font-size:15px}.topic-option{font-size:15px;padding-left:12px}.topic-options{border-radius:15px}}

.request-switch{display:flex;gap:12px;flex-wrap:wrap;margin-bottom:28px}.formcard fieldset{border:1px solid #d7e6f0;border-radius:16px;padding:20px;margin:20px 0;min-width:0}.formcard legend{font-weight:700;padding:0 8px}.formcard [hidden]{display:none!important}.formcard input[type=tel]{width:100%;box-sizing:border-box}.formcard .check{align-items:flex-start}

/* Version 31: consultation forms, privacy dialog and urgent-care alert */
.request-switch{display:flex;flex-wrap:wrap;gap:10px;margin-bottom:24px}
.request-switch .btn.outline{background:#fff;color:var(--blue);border:1px solid #c9d9e8}
.request-switch .btn:not(.outline){background:var(--blue);color:#fff;border:1px solid var(--blue);box-shadow:0 5px 16px rgba(31,100,151,.2)}
.required-mark{color:#d52f3f;font-weight:800;margin-left:3px}
.formcard label:has(> .required-mark){position:relative;display:flex;flex-wrap:wrap;align-items:baseline;column-gap:2px}
.formcard label:has(> .required-mark)>input,.formcard label:has(> .required-mark)>textarea,.formcard label:has(> .required-mark)>select{flex:0 0 100%;margin-top:5px}
.formcard label .fine{flex-basis:100%;font-weight:400;margin:0}
.formcard .consent-check{align-items:flex-start;line-height:1.55}
.formcard .consent-check .required-mark{margin-right:4px}
.urgent-callout{background:#fff0f0;border:2px solid #d72e3e;border-left:8px solid #d72e3e;border-radius:14px;padding:22px 24px;box-shadow:0 6px 22px rgba(176,30,45,.12)}
.urgent-callout b{color:#a91524;font-size:19px}
.urgent-callout p{color:#5e2630}
.privacy-modal{width:min(860px,calc(100vw - 28px));height:min(82vh,800px);padding:0;border:0;border-radius:16px;box-shadow:0 20px 70px rgba(9,32,57,.35);overflow:hidden}
.privacy-modal::backdrop{background:rgba(13,31,52,.64);backdrop-filter:blur(2px)}
.privacy-modal-head{height:58px;display:flex;align-items:center;justify-content:space-between;padding:0 18px 0 24px;color:#19385d;border-bottom:1px solid #dce7f0;background:#f7fbff}
.privacy-modal-close{border:0;background:#e7f1f8;color:#19385d;border-radius:50%;font-size:26px;line-height:1;width:36px;height:36px;cursor:pointer}
.privacy-modal iframe{display:block;width:100%;height:calc(100% - 58px);border:0;background:#fff}
@media(max-width:600px){.request-switch .btn{flex:1 1 100%;text-align:center}.privacy-modal{height:88vh}}

/* v33: keep the required marker beside the field title */
.formcard .field-title{display:block}.formcard .field-title .required-mark{display:inline;margin-left:3px}